FBP1 and fructose-1,6-bisphosphatase deficiency: Fructose-1,6-bisphosphatase (FBPase) deficiency (FBP1D, OMIM: 229700 OMIM, 2021) is an inherited autosomal recessive (AR) disease caused by the FBP1 gene mutations, which leads to the FBPase reduction or deficiency (Bhai et al., 2018; Zahoor et al., 2020).