GPX4 and neoplasm: Similarly, in papillary thyroid cancer, the circKIF4A/miR-1231/GPX4 cascade [117], in PrC, the miR-15a/GPX4 cascade [118], in HCC, the circIL4R/miR-541-3p/GPX4 cascade [119], and in non-small cell lung cancer (NSCLC), the circDTL/miR-1287-5p/GPX4 cascade [120], all regulate the ferroptosis process in their respective tumor types.