Although alpha‐synuclein amyloid is not transmissible like prions, evidence suggests the existence of diverse conformers or strains with distinct structural and biochemical properties, different seeding activities, and varying propagation patterns,56 which could contribute to the heterogeneity of neurodegenerative symptoms and disease progression rates observed in synucleinopathies.57 This evidence concerns the gene SNCA and synucleinopathy.