Moreover, an NP study of Yinchen Wuling San, a complex medical prescription comprising six medicinal plants used for cancer treatment, revealed that the genes TNF, AKT1, and EGFR are targeted by the bioactive compounds of Yinchen Wuling San against HNSCC (Zhang et al., 2022). The gene discussed is EGFR; the disease is head and neck squamous cell carcinoma.