PTGES2 and cutaneous melanoma: Similarly, BCC, malignant neoplasms of skin, and body-mass index (BMI, a quantitative endpoint) showed significant associations with PTGES2 as the top three most significant phenotypes in the UKB-PPP (9,621 protein-phenotype pairs) and deCODE (9,620 protein-phenotype pairs) studies (Figures 4A,B; Supplementary Tables S13, S14).