Furthermore, FDR-corrected p-value <0.05 was observed for gamma-enolase (ENO2) and heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (HS3ST3B1) with BCC, with OR values <1 indicating a protective effect against BCC (Figure 2D; Supplementary Table S6). Here, HS3ST3B1 is linked to skin basal cell carcinoma.