EPB41 and deep vein thrombosis: In VITT03, in whom a deep vein thrombosis was observed, a missense VUS [c.1228G>T(p.Asp410Tyr)] classified by all in silico predictors as damaging has been identified in EPB41 gene, encoding for a structural element of the erythrocyte membrane skeleton, for which gene expression studies evidenced its contribution in the thrombus formation network [54].