This is a method called immunoradiation therapy, in which irradiation is not aimed at cancer necrosis but rather to elevate anti-tumor immune response through damage to cancer cell genes and the generation of cancer-specific antigens in the repair process and exposure of cancer antigens stored inside cancer cells by increased expression of MHC (major histocompatibility complex) class 1 on the cell membrane [13,14]. Here, HLA-C is linked to neoplasm.