Figure 4 (MOC2-CIITA) shows the MHC-II cell surface expression of MOC2-CIITA compared to the parental untransfected control (MOC2-pc). Of note, MOC2-CIITA transfected cell line did not express PD-L1, differently from results obtained in parental cell line after treatment with IFN-γ (Figure 4, MOC2-pc, bold line). It should be emphasized that stable expression of CIITA in MOC2 tumor cells did not affect their growth rate in vitro (Supplementary Figure S3). Here, CIITA is linked to neoplasm.