As shown in Supplementary Table 1, there are currently few reports of non-bacterial cystitis caused by ICIs for cancer treatment, including anti-PD-1 and anti-PD-L1 in patients with lung cancer (8/10), intrahepatic cholangiocarcinoma (ICC) (1/10), and advanced breast cancer (1/10). The gene discussed is PDCD1; the disease is intrahepatic cholangiocarcinoma.