Moreover, tumor intrinsic FAK inhibition in mouse ovarian or SCC models results in enhanced T and B cell recruitment, potentiated activity of immune checkpoint antibodies and formation of tertiary lymphoid structures, which are known markers of immune activation (Canel et al., 2020; Ozmadenci et al., 2022; Serrels et al., 2015, 2017). The gene discussed is PTK2; the disease is neoplasm.