IL10 and inflammatory bowel disease: Interestingly, maternal antibiotic-perturbed microbiota has been shown to exacerbate gut inflammation when transferred to mouse pups deficient in the anti-inflammatory cytokine interleukin 10 (IL10−/−),24 and antibiotic usage has been significantly associated with an increased risk of new-onset IBD,25 indicating a connection between antibiotic use, microbiome composition and gut health.