GBA1 and Parkinson disease: Dysautonomia was tested using the COMPASS-31 scale in 16 GBA1-PD subjects and 18 randomized PD patients with negative genetic test, with comparable demographic data, disease onset, duration and LEDD; mean total score was significantly higher in GBA1 patients (34.1 vs 20.2, p 0.03), indicating a higher burden of dysautonomia.