Morisawa and coworkers showed a role for IL‐18 in the development of pulmonary hypertension related to lung disease and hypoxia by attenuated hypoxic pulmonary hypertension in mice with IL‐18 disruption (Morisawa et al., 2016), and in transgenic mice that overproduced mature IL‐18, Hoshino et al. Here, IL18 is linked to lung disorder.