SOAT1 and acute lymphoblastic leukemia: Again, only the GSEA signature for the JAK/STAT pathway showed a confidence rate above 95% and was significantly enriched in cells transduced with JAK3Q988P compared to cells transduced with the empty vector (Fig. 1e, f), recapitulating the results previously obtained from the comparison between patients with JAK/STAT pathway mutations and the rest of T-ALL/LBL patients.