PHLDA2 and nonpapillary renal cell carcinoma: In this study, the methylation status of PHLDA2 was investigated, and we found that, compared to normal tissues, several probes, including cg05167973, cg04720330, cg21259253, cg16057921, cg07482372, cg15658784, cg01691090, was hypomethylated in ccRCC.