Finally, we found cis-enhancer hijacking events activating potentially novel oncogenes such as ID4 in the prostate cancer cell line VCaP and TXLNA in the small cell lung cancer cell line CORL88 (Fig. 2E), which are likely caused by large deletions based on the known patterns of structural variants in the HiChIP signal (Figure S2B–D). Here, ID4 is linked to Familial prostate cancer.