NEAT1 and myeloid leukemia: We demonstrate that CRISPR-Cas9–mediated genomic deletion of the NEAT1 PAS diminishes NEAT1_1 levels, which is accompanied by a significant increase in NEAT1_2 in GBM cells (Fig. 2), similar to previous studies which deleted the NEAT1 PAS in the human myelogenous leukemia haploid cell line HAP1 (29).