The functions of various DC subsets in anti‐tumor immunity are different.[26] According to the function and genetic basis, cDCs can be classified into CD8+ DC and CD11b+ DC subsets.[27] As shown in Figure 6B, ME49Δompdc/gra4 infection leads to increased differentiation of primary DCs into CD11b+ DCs in the spleens of WT mice, no such effect was observed in the Ifnar−/− mice. The gene discussed is IFNAR1; the disease is neoplasm.