VEGFA and macular retinal edema: Intravitreal injections of anti‐VEGF medicines are effective in treating macular edema and improving vision in cases with pre‐proliferative or proliferative diabetic retinopathy.[18] In advanced DR patients experiencing intravitreal hemorrhage and neovascularization, vitrectomy can be performed as a preventative measure against vision loss and visual field defects.[19] While these treatment modalities have been widely adopted in clinical practice, their effectiveness remains suboptimal in some patients, and they are not without limitations.