HNF1B GGG haplotype in European population associated with prostate and endometrial cancers, CLPTM1L GCG haplotype in European population associated with skin and lung cancers, CASC8 GT haplotype in European populations associated with colorectal and prostate cancers, DIRC3 GC haplotype in European population associated with breast and thyroid cancers, and BABAM1(C19orf62) GT haplotype in European population associated with breast and ovarian cancers. The gene discussed is CASC8; the disease is thyroid cancer.