PTGS2 and neoplasm: The COX2‐PGE2 pathway plays a critical role in the induction of inflammatory cytokines that contribute to tumor progression via multiple mechanisms.[19] We observed much lower PGE2 concentrations in the medium of CT26 cells after incubating them with the Trp complex, compared to scrambled miR, miR‐193a‐3p and miR‐103‐3p/miR‐107‐3p mimic treatments alone.