CYP27A1 and metabolic dysfunction-associated steatotic liver disease: Several studies have shown that the expression of CYP7A1 and LXRα was increased, CYP27A1 and FXR was decreased in the NAFLD model,14, 33 and our result indicated that CYP7A1, CYP27A1, FXR, and LXRα expression were increased after SG treatment.