Zaharieva et al. in a study of 2317 bladder cancer samples found MYC copy number gains in 10.5% of pTa, 15.8% of pT1, 21.4% of pT2–4, as well as in 5.7% of G1, 11.9% of G2 and 19.7% of G3 urothelial carcinomas [156]. This evidence concerns the gene MYC and urothelial carcinoma.