Similarly, SCL/TAL1 interrupting locus (STIL), an important checkpoint protein that is involved in the regulation of centriole duplication, is also highly expressed in bladder cancer, and it was reported that STIL enhanced the PI3K/AKT/mTOR pathway resulting in increased MYC expression, thereby promoting the development of bladder cancer [140]. Here, AKT1 is linked to urinary bladder carcinoma.