AFP and neoplasm: In fact, the significant prognostic factors for higher mortality were age greater than ≥ 65 years (HR 1.55), cirrhosis (HR 1.46), larger tumor size (HR 1.09 per 1 cm increase), advanced tumor stage (HR 1.61, 3.45, and 3.49 for stage II, III, and IV, respectively), α-fetoprotein (AFP) greater than 400 ng/ml (HR 1.25), and hemoglobin ≤ 10 g/dL (HR 1.54).