Nuclear localization of tetraspanin 8 was observed in several cell lines, including SW1990 (pancreatic cancer), MDA‐MB‐231 (breast cancer), SW620 (colon cancer), HGC‐27 and AGS (stomach cancer), and also U‐87 MG and U251 MG (glioblastoma cell lines). This evidence concerns the gene TSPAN8 and familial pancreatic carcinoma.