TGFB1 and gastric cancer: In GC, lncRNA MACC1-AS1 is induced by transforming growth factor β1 (TGF-β1) secreted by mesenchymal stem cells (MSCs), which suppresses the expression of miR-145-5p (the stemness & chemoresistance inhibitor) to accelerate FAO-dependent (fatty acid oxidation) stemness and chemotherapeutic resistance of GC cells [29].