Figure 3A indicated that the main form of alteration in the PHF5A gene was amplification, and the top 5 cancers in terms of PHF5A mutation frequency were non-small cell lung cancer (15.22%), endometrial cancer (10.00%), soft tissue sarcoma (8.82%), melanoma (8.41%) and breast cancer (5.69%). Here, PHF5A is linked to soft tissue sarcoma.