AKT1 and urinary bladder carcinoma: Similarly, transcriptome analysis of bladder cancer tissues revealed high expression of MYDGF (Zhu et al. 2011), which can promote cancer cell proliferation, migration and invasion, and promote malignant behavior and epithelial-mesenchymal transition (EMT) in human bladder cancer by regulating the PI3K/AKT and Wnt/β-catenin pathways (Li et al. 2021).