MYDGF was identified in synovial fibroblast-like synovial cell proteins from patients with rheumatoid arthritis, which were distributed in the perivascular and synovial lining in synovial sections from rheumatoid arthritis and osteoarthritis patients (Dasuri et al. 2004; Weiler et al. 2007). This evidence concerns the gene MYDGF and rheumatoid arthritis.