A comprehensive literature review of reported STAT5b::RARα positive APL cases, of which there were only 18, conducted by Zhang et al. [19] reported a median age at diagnosis of 39 ranging from 17 to 67 years of age and a greater propensity in the male population (15 patients were male and 3 were female). This evidence concerns the gene STAT5B and acute promyelocytic leukemia.