Therefore, we generated two sets of CyCMV vaccine vectors expressing influenza antigens, one set based on FL CyCMV to induce MHC-Ia-restricted CD8 + T cells, and another based on dd CyCMV to induce MHC-II- and MHC-E-restricted CD8 + T cells (Supplementary Fig. 1A–C). Here, CD8A is linked to influenza.