Consistent with previous results, PART1, miR-490-3p and SLC7A1 were found to be aberrantly expressed in HCC and both were observed to be associated with poor prognosis in patients with HCC; thus, dysregulation of the PART1/miR-490-3p/SLC7A11 axis could serve as a diagnostic and prognostic marker for patients with HCC. This evidence concerns the gene PART1 and hepatocellular carcinoma.