POU2AF1 and Miyoshi myopathy: We also demonstrate that mSWI/SNF ATPase degraders possess potenttherapeutic activity against subsets of MM and DLBCL cells reliant on POU2AF1.Typically, POU2AF1 functions as coactivator of the POU2 family of transcriptionfactors, pivotal in orchestrating B cell development and the tumorigenesis of B cellmalignancies.