Sepsis patients are attacked by bacteria or other pathogens, resulting in dysregulation of the systemic inflammatory response, destruction of tissue cell integrity, and LDH release into the blood, significantly increasing serum levels.[32] LDH not only reflects the body inflammatory state but also has the value of monitoring the development of sepsis in microcirculation metabolism to a certain extent.[33] Mast cell-expressed membrane protein 1 (MCEMP1) is involved in the regulation of mast cell differentiation or innate immune responses. This evidence concerns the gene MCEMP1 and Sepsis.