Some scholars have established a mouse model of sepsis induced by cecal ligation and puncture to determine the expression of MCEMP1 and observed that MCEMP1 is highly expressed in septic mice.[34] Loss of MCEMP1 can promote the activity of T lymphocytes and NK cells, increase the expression of immunoglobulin, inhibit the release of inflammatory cells, and reduce the apoptosis of T lymphocytes.[34] In our study, the same results were obtained, and these 3 diagnostic genes (CD177, LDHA1, and MCEMP1) were all highly expressed in sepsis patient samples. Here, MCEMP1 is linked to Sepsis.