AKT1 and cancer: The disruption of the IL-6 signaling pathway has been associated with the pathogenesis of various diseases, including autoimmune diseases, cancer, cardiovascular diseases, and neurological disorders.[32] AKT1 is a key cell signaling molecule that plays a crucial role in maintaining normal physiological function and preventing disease development, particularly in the processes of vascular endothelial cell proliferation, migration, survival, and cardiomyocyte survival.