The percentage of CD4+CD70+ and CD8+CD70+ T cells was 9.6-fold and 4.2-fold higher in patients with severe aGVHD (25% and 13%; Figure 4A) than patients with no GVHD (2.6% [P < .005] and 3.1% [P < .05], respectively). This evidence concerns the gene CD70 and graft versus host disease.