To identify molecular pathways that are differentially regulated in the context of BRCA1 or BRCA2 mutation in ovarian cancer, we compared the transcriptomic profile of ovarian tumors obtained from patients with HR WT (HRwt; n = 375), BRCA1-mutant (BRCA1mt; n = 16), and BRCA2-mutant (BRCA2mt; n = 15) HGSOC (Table 1). The gene discussed is BRCA1; the disease is ovarian carcinoma.