Higher IAPP staining was observed in the insulinoma cells of patients 3 and 6 (Figure 1H and K, respectively) than in those of patients 1 and 4 (Figure 1F and I, respectively) or in patients 2 and 5 (Figure 1 G and J, respectively), both of whom had no history of hypoglycemic coma. The gene discussed is IAPP; the disease is pancreatic insulinoma.