Within the Leishmaniasis pathway, members of the Toll-like receptor signaling pathway (TLR2, TLR4, MYD88, NFKBIA, NFKB1, and RELA) were all downregulated in neutrophils following L. infantum infection, and co-expressed with our 5 downregulated lncRNAs (LINC01093, MIR3945HG, SERPINB9P1, SLC39A13-AS1, and PELATON). This evidence concerns the gene TLR4 and leishmaniasis.