For those downregulated transcripts in infected neutrophils, potential target genes of upregulated miRNAs, 181 pathways were enriched (FDR≤0.05), highlighting the Leishmaniasis Pathway, and several other inflammatory pathways such as Antigen processing and presentation, Toll-like receptor signaling pathway, NF-kappa B signaling pathway, JAK-STAT signaling pathway, among others. This evidence concerns the gene SOAT1 and leishmaniasis.