INS and diabetes mellitus: The glycated serum protein (GSP) levels were reduced by 18.6% (p < 0.01), 31.7% (p < 0.01), and 29.0% (p < 0.05) in the MFP50, MFP90.Relative to the DM group, the Fasting serum insulin (FINS) of both the MFP50 (p < 0.05) and MFP90 (p < 0.01) groups were significantly reduced.The HOMA-IR values of the MFP90 group (4.35 ± 1.62) were markedly lower than that in the metformin group (4.70 ± 2.43).MFP50 and MFP90 showed better effects than the metformin group in terms of the recovery of STZ-induced impairment of pancreatic islets (40 mg/kg).