CCR2 and myocardial infarction: In human hearts, the presence of CCR2+ macrophages (derived from circulating monocytes) is associated with worse ventricular function and adverse remodelling.168 Monocytes biased towards pro-inflammatory processes might be recruited not only to the infarct zone, but also to the remote myocardium, which could partially explain why people with DM are more likely to develop HF after MI.169,170 Furthermore, recent evidence suggests that inflammatory cells can be a determinant of arrhythmia after MI.171