Other studies have shown that TRPV5 and TRPV6 are expressed in leukemia cell K562, and the increase in channels activates Ca2+/calmodulin-dependent kinase II (CaMKII), thereby increasing intracelluar Ca2+, regulating cell proliferation, differentiation, and resistance to apoptosis [50,51]. Here, TRPV6 is linked to leukemia.