Different serum, salivary, and gingival crevicular fluid biomarkers have been evaluated to assess the presence and intensity of inflammation in the oral surgical area.5,6 Among these, interleukin-1β, interleukin-6, tumor necrosis factor-α, C-reactive protein (CRP), and white blood cells can be mentioned.5,7 According to previous studies, inflammatory biomarker levels in saliva and serum change due to chronic periodontitis or peri-implantitis.8 Moreover, Chaushu et al9 demonstrated a strong correlation between blood cell counts and peri-implantitis. This evidence concerns the gene IL6 and Peri-Implantitis.