Two lncRNA/miR-545-3p/PCG axes can suppress cancer progression, including the LINC01410/miR-545-3p/HK2 axis in neuroblastoma (NB) to suppress tumorigenesis and tumor radioresistance5 and the LINC00261/miR-545-3p/MT1M axis to suppress cisplatin resistance in esophageal squamous cell carcinoma (ESCC) cell lines.43 This evidence concerns the gene HK2 and esophageal squamous cell carcinoma.