Additionally, miR-545-5p promotes cancer cell invasion and migration by targeting six genes: CCND2 in NPC,44SSFA2 in LC,36c-MET in NSCLC,45CNPY2 in GC,61MDM2 in CRC,48 and DIMT1 in SaOS.9 This evidence concerns the gene CCND2 and colorectal carcinoma.