The MDR analysis showed a simultaneous strengthening ofeffects between two loci, APEX1 (rs1130409) (H = 0.07 %) and SOD2 (rs4880) (H = 0.55 %), and also independenceof their effects from САТ (rs1001179) (H = 0.44 %) duringformation of luminal B Her2-negative BC (Fig. 2). This evidence concerns the gene APEX1 and breast cancer.