Several frameshift, missense, and nonsense mutations in the gene coding for Aryl hydrocarbon-interacting protein-like 1 (AIPL1) are reportedly associated with autosomal recessive Leber congenital amaurosis type IV (LCA4) (OMIM #604393) (111, 112). This evidence concerns the gene AIPL1 and Leber congenital amaurosis 4.