confirmed that LINC021 is significantly upregulated in CRC cell lines and clinical tissues, and showed that the oncogenic LINC021 specifically binds with the m(6)A “reader” IMP2 protein, enhancing the mRNA stability of MSX1 and JARID2 through m(6)A regulatory mechanisms during CRC tumorigenesis and pathogenesis (144). Here, JARID2 is linked to colorectal carcinoma.