Mechanistically, LINC01088 directly binds to miR-548b-5p and miR-548c-5p, with miR-548c-5p significantly upregulating the expression of Ras GTPase activating protein binding protein 1 (G3BP1) and programmed death ligand 1 (PD-L1), thereby regulating CRC cell migration and invasion (145). This evidence concerns the gene CD274 and colorectal carcinoma.