Utilizing data from Timer2.0, we discovered a significant association between MVP expression levels and a cohort of TIICs, and of particular note, Th17 cells may tend to promote tumor cell proliferation by releasing interleukin-17 (IL-17) (32), which imply that MVP might facilitate tumorigenesis and aggravation in PAAD. Here, IL17A is linked to pancreatic adenocarcinoma.