MKI67 and ovarian cancer: Multivariate analysis further showed that breast/ovarian cancer family history (OR = 2.15, 95%CI 1.10–4.19, P = 0.025) and high Ki-67 levels (OR = 2.91, 95%CI 1.20–7.07, P = 0.018) were two independent predictive factors for BRCA mutation.