A previous study from a type 2 diabetic mouse model showed that the GFAP levels in the colon, the amygdala, and the prefrontal cortex were significantly increased compared to healthy mice, and supplementation with an unknown strain of L. plantarum combined with inulin resulted in a significant decrease in GFAP levels in all three sites (44). Here, GFAP is linked to type 2 diabetes mellitus.