The results from Cox regression analyses, as manifested in Table 2, indicated a significantly positive association between cumulative AIP and stroke in model 1 (HR = 1.76, 95%CI: 1.20–2.59, p = 0.004) as well as model 2 (HR = 1.75, 95%CI: 1.15–2.66, p = 0.009), and the correlation remained marginal significant in model 3 (HR = 1.53, 95% CI: 1.00-2.35, p = 0.063). The gene discussed is AIP; the disease is stroke disorder.