Continuous cumulative AIP was positively correlated with MACE in crude model (model 1), model 2 which adjusted for demographic covariates and model 3 which further adjusted for more confounders including age, gender, BMI, current smoking status, cardiovascular disease, hypertension, diabetes mellitus, antihypertensive drugs, antidiabetic drugs, lipid-lowering drugs, LDL-c, and eGFR (p < 0.05 for each model). The gene discussed is AIP; the disease is hypertensive disorder.